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The nominees were announced by Cazwell and Amanda Lepore. Hosts were Candis Cayne and Colman Domingo. Other musical acts were, The Cliks, Dangerous Muse, Cyndi Lauper.
Michelle Williams, of Destiny's Child, introduced Lady Gaga before her performance of "Just Dance".
- Set list
|Lady Gaga||Always Next, Forever Now Award||Won|
|BTW Foundation||Most Innovative Charity||Won|